Category Archives: Drugs

Diet, Diet, Drugs

Weight Loss Pill Lorcaserin Does Not Increase the Risk of Cardiovascular Problems

Weight loss drug Lorcaserin has proven efficacy for weight loss in overweight/obese adults.bmi obesity

The medicine works by suppressing appetite and should be taken twice a day. It costs around $220-290 (£155-225) per month in the US.

Scientists also found that Lorcaserin did not raise the risk of cardiovascular problems.

12,000 obese/overweight adults who suffer from atherosclerotic cardiovascular disease or multiple cardiovascular risk factors took part in the study. They were given Lorcaserin 10mg twice daily or placebo (a substance that is made to resemble Lorcaserin but do not contain the active ingredient).

The results showed that those taking Lorcaserin 10mg lost an average of 4kg over 40 months without the risk of further heart problems.

Lorcaserin is currently available in the US under the name Belviq.

The drug is not available in the UK or EU, as it would need a European license and be approved by NICE before doctors can start to prescribe Lorcaserin.

Xenical and Alli are weight loss treatments currently available in the UK.

To read more about Xenical and Alli and for a free private online consultation (with a UK GMC-registered doctor) for weight loss medication, please go to www.ukmeds4u.com.

It is estimated that 1 in 4 adults in the UK are overweight/obese.

To read more about the study, CLICK HERE

Drugs, General, Mens Health

Could Metformin Prevent Type 1 Diabetes?

Children who are at risk of developing type 1 diabetes will trail metformin to see if the cheap drug can prevent the disease.

The study will take part in Scotland which will involve children, aged 5 to 16, taking a simple blood test to determine whether they are at risk of developing the condition.

Scotland has the third highest rate of type 1 diabetes in the world.

If they are found to be at risk then they will be given the chance to take part in a clincal trail.

Metformin is the worlds most common prescribed medicine for diabetes.

The study will test whether metformin can stop the immune response from destroying beta cells.

Professor Wilkin, of the University of Exeter Medcial School, said: ‘We still have no means of preventing type 1 diabetes which, at all ages, results from insufficient insulin.

‘We all lose beta cells over the course of our lives, but most of us have enough for normal function.

‘However, if the rate of beta cell loss is accelerated, type 1 diabetes develops, and the faster the loss, the younger the onset of the condition.’

It has been estimated that 80,000 children worldwide develop type 1 diabetes each year.

Diabetes can lead to other health problems such as heart disease, kidney failure and erectile dysfunction in men.

To read more CLICK HERE

If you have any concerns regarding diabetes then you should speak to your GP.

If you suffer from erectile dysfunction then visit www.ukmeds4u.com for your free online private consultation.

 

Drugs, General, Mens Health

Good News For Those Who Suffer From The Side Effects Of Statins

Repatha could be the new medication to help lower cholesterol since statins were invented in the 1980s.repatha

The drug will be the first alternative treatment to be available on the NHS for people who react badly to the side effects of statins.

Researchers have revealed that between 5% and 20% of people have to stop taking statins due to muscle pain.

A trail was carried out on 491 patients who have reported of suffering from muscle pain while taking statins.

To test whether statins were really having a side effect, half of the participants were given statins again and the other half were given a placebo pill, a tablet that does not contain an active drug ingredient.

The results showed that 40% of those given the statins developed ‘intolerable’ muscle pain.

218 people participated in a second trail, where they was given Repatha or the older drug, ezetimibe.

Only 13% of people who were given Repatha reported muscle pain and just one patient stopped taking the medicine due to the muscle pain being unbearable.

There are other prescription medicines available  to treat high cholesterol but like statins, and every other medicine, they come with side effects such as erectile dysfunction.

To read more CLICK HERE

For more information about high cholesterol CLICK HERE

If you have any concerns regarding statins or high cholesterol, please see your GP.

If you think you have erectile dysfunction, please go to www.ukmeds4u.com for your free e-consultation.

Drugs, General

Could Sildenafil Increase Skin Cancer Risk?

Sildenafil, the active ingredient in Viagra, was originally developed to treat heart conditions, but during original trials it was found to be more effective at treating erectile dysfunction (also known as impotence).sildenafil

But now, scientists have warned that the drug could increase the risk of melanoma – the deadliest form of skin cancer.

Researchers at the University of Tübingen in Germany have discovered that Sildenafil can encourage tumors to grow more rapidly.

A recent study found that Sildenafil can stimulate skin cancer growth.

Sildenafil has a stimulating effect on the messenger molecule cyclic guanosine monophosphate (cGMP), which promotes the growth of existing malignant melanomas.

The scientist came to this conclusion through animal experiments and human cell cultures.

Cells normally contain an enzyme called phosphodiesterase type 5 (PDE5), that ensures the newly-formed cGMP is continuously broken down.

But, Sildenafil belongs to a group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors.

Study author Professor Robert Feil said: ‘Taking sildenafil basically disables this brake.’

Consequently, the melanoma begins to grow more aggressively.

However, the study noted that there is no reason for men to stop taking PDE5 inhibitors to treat erectile dysfunction.

The researchers also have to take into account that the possibility that a higher incidence of skin cancer may be due to lifestyles, including sunbathing on holiday.

Professor Feil warned: ‘Ultimately, we should all be thinking about reducing our risk of skin cancer and cutting our exposure time to the sun, as well as using effective UV protection.’

Sildenafil is marketed as Viagra and was approved by FDA (The Food and Drug Administration) on 27th March 1988. Pfizer’s patent on Sildenafil expired on 21 June 2013.

If you are concerned that Sildenafil (Viagra) could increase the risk of skin cancer then there is other alternative prescription only  medication for erectile dysfunction such as Cialis and Levitra.

For further information about Sildenafil (Viagra) and other erectile dysfunction medication, please go to www.ukmeds4u.com.

To read the full article, please click here.

 

Drugs, Erectile dysfunction

Could Cialis Be Effective In Treating Cancerous Tumours?

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cialis 20mgA clinical trial is underway which will hopefully show that Cialis weakens the ability of a tumour to fight the human immune system.

The trial is specifically focusing on those people suffering from tumours in the head and neck.

Professor Joseph Califano from the Department of Otolaryngology, Head and Neck Surgery at Johns Hopkins Hospital explained that a suppressed immune system could be the reason why these tumours respond so aggressively. He added that Cialis could prevent the immune system from producing nitric oxide which was being used by the tumours to create a shield to protect them.

It is hoped that Cialis will help the body to fight tumours on its own and cause them to shrink and possibly disappear.

Other research has already been done using Viagra for cancer treatment by Professor Ivan Borrello , a colleague of Dr. Califano. They have been working together on other studies using mice but reportedly prefer using Cialis because it works for longer period before wearing off.

One of the great advantages of using Cialis to treat head and neck tumours is that the drug is safe and its side effects are minimal.  In fact it was even noted that when compared to radiotherapy or chemotherapy the side effects of Cialis were significantly more pleasant!

Obviously the Cialis will not cure cancer alone but it could be used as a complementary treatment alongside standard cancer therapies.

Both men and women are being enrolled into the clinical trial which has been funded by the National Cancer Institute in America. It is hoped that the daily doses of Cialis over the two week trial period will boost the immune systems of the participants.

Dr. Califano mentioned that the male participants were very happy about the idea of being given Cialis as part of their treatment for cancer.

For more information about erectile dysfunction or prescription only medicine such as Cialis, please go to: www.ukmeds4u.com

Drugs, Erectile dysfunction, Viagra

Over-The-Counter Supplements May Be Unsafe

Around 40-70% of men will experience sexual dysfunction at some point in life. herbal viagra

To avoid the embarrassment of speaking to their doctor or paying for a prescription, many buy over-the-counter (OTC) products.

However some over-the-counter drugs which are sold as alternatives to prescription only medication (POM) actually contain the active ingredients of the prescription only drugs.

It has been found that an OTC product was advertised as “natural” but contained Sildenafil, the same ingredient found in the prescription only medicine Viagra which is used to treat erectile dysfunction (ED).

Sildenafil belongs to a group of medicines called phosphodiesterase-5-inhibitors (PDE5Is).

PDE5is cannot be legally sold over-the-counter as taking them without doctors supervision can be dangerous for someone with an undiagnosed cardiac condition, and other conditions such as high or low blood pressure.

For more information about erectile dysfunction or POMs available please go to: www.ukmeds4u.com

To read the full article, please go to: http://www.medicalnewstoday.com/articles/305124.php

Drugs

Existing indigestion drug could help to fight cancer!!

A common drug that is used everyday by millions of people to combat indigestion has now been found to possess anti-cancer properties which researchers are claiming could help in the fight against cancer.

Which one?

The drug in question is a drug called Cimetidine, and is at present used as a treatment for indigestion and other gastric related conditions such as gastroesophageal reflux disease (GERD) and gastric ulcers.

Could it fight cancer?

In a recent study done by Dr Pan Pantziarka for the Re-purposing Drugs in Oncology (ReDO) project he found that Cimetidine may be able to block histamine receptors in any cancerous cells that may be found, and in turn would be able to assist the immune system’s fight against the cancerous cells.

Studies have shown a drastic impact for patients who had gastric cancer, melanoma and renal cell carcinoma who were given Cimetidine as a supplement to the other standard drugs that are used in the battle against cancer.

Why aren’t we already using it?

When Cimetidine was first produced and tested, it’s primary purpose was to help fight gastric conditions, but due to the long process that is required to create, test and market a new drug, the ReDO project was created to check existing drugs to see if they had properties that could be used to fight other conditions than their primary target.

Although ReDO have found that Cimetidine can help in the fight against cancer,  due to all the red tape there is in the medical world, it is not easy for them to get it back into the testing lab and get it properly tested in clinical trials

So… What do you think?

Do you think that we should be getting this drug retested to try and help in the fight against cancer?

Let us know what you think below…

 

Drugs

Breaking News – Worldwide Crackdown on fake prescription drugs

The Medicines and Healthcare products Regulation Agency (MHRA) says more than a million doses of fake prescription drugs worth approximately £2m have been seized from the UK’s postal service and ports during its latest crackdown.

Packages from Australia, Canada and New Zealand have been stopped and searched at several major international airports such as New York, Chicago, London, Manchester and Sydney.

viagra-thumb

Fake Drugs Seized!

Almost 20,000 packages were seized during the operation. The seized packages contained fake prescription drugs from countries such as China, India, Mexico and Singapore.

Investigations at Heathrow and Manchester found over 1000 packages containing illegal prescription medication purchased through online retailers claiming to be branded drugs.

Some of the drugs ordered were bimatroprost (Glaucoma Eye drops), Insulin, Tramadol, Tadalfil and Sildenafil Citrate (Viagra).

What happens if you take fake drugs? 

If you purchase drugs on-line, you have no guarantee that the medicines will actually be the ones that you receive, or that they will even contain the correct active ingredient. So, there seems to be a clear choice between a drug not working or even making you very ill! You also forfeit legal backup if you experience a reaction, or if they have no medical effect on you.

Internet Service Providers for nearly 2000 individual websites were also contacted to try to stop the flow of fake drugs.

Is it really  worth the risk?

Many online pharmacies offer empty promises that the drugs they sell at cheap rates are legitimate drugs at cheap prices, when in fact they are just cheap imitations that will probably have little to no effect at all.

Be safe – and only go to reputable on-line pharmacies that are easy to contact and transparent in their approach.

UKMeds4U only offer genuine UK/EU-sourced branded prescription-only medication (such as Cialis, Levitra, and Viagra), and will NOT dispense any POMs without first issuing a private prescription (where suitable) by a UK GMC-registered doctor.